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Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors (3,4). It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system (1-6). Factor XIIIa has also been used with CD34 to Factor XIIIa is a blood proenzyme that has been identified in platelets, megakaryocyte, and fibroblast-like mesenchymal or histiocytic cells present in the placenta, uterus, and prostate; it is also present in monocytes and macrophages and dermal dendritic cells. Platelet factor XIII is comprised only of 2 A subunits, which are identical to those of plasma origin. Upon cleavage of the activation peptide by thrombin and in the presence of calcium ion, the plasma factor XIII dissociates its B subunits and yields the same active enzyme, factor XIIIa, as platelet factor XIII. Factor XIIIa Positive Control Slides , Product No. 251S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections). Preparation Note Download the IFU specific to your product lot and format Note: This requires a keycode which can be found on your packaging or product label.
Common Pitfalls [edit | edit source] Not specific for dermatofibroma. References [edit 产品ID factor-xiiia. XIIIa因子，又称纤维蛋白低聚酶和纤维蛋白稳定因子，是凝血级联中产生的最后一种酶。. 它是一种钙依赖的谷氨酰胺转胺酶或转胺酶，在纤维蛋白分子间形成-谷氨酰胺-爱塞隆-赖氨酸交联，从而使纤维蛋白凝块的机械稳定性及其对蛋白水解的抵抗力。.
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Cited in 1 reference(s). Definition / general Fibrohistiocytic marker; note that peritumoral cells may also exhibit Factor XIIIa staining Also active form of factor XIII, an enzyme of coagulation system that crosslinks fibrin (Wikipedia: Factor XIII [Accessed 2 August 2018]) Stabilization of Fibrin The conversion of soluble fibrin to an insoluble fibrin clot is catalyzed by the transamidase factor XIIIa. Lysine and glutamine side chains of α- and γ-chains of fibrin are crosslinked to form homopolymers.
Fil:Human factor XIII 1EVU.png – Wikipedia
Updated On: 30-6-2020. 150.4 K. like. 7.5 K. dislike. 1x 1.5x 22 Jul 2020 Factor XIII Deficiency | Fibrin Stabilizing Factor Defect | Hematology. Factor XIII (also known as Fibrin stabilizing factor) is the proenzyme (zymogen) of a glutaminase, which is activated by thrombin.
Factor xiiia synonyms, Factor xiiia pronunciation, Factor xiiia translation, English dictionary definition of Factor xiiia. Noun 1. factor XIII - in the
Factor XIIIa has also been used with CD34 to differentiate between dermatofibroma and dermatofibrosarcoma protuberans. Specimen Requirements . A formalin-
5 Mar 2021 Complete information for F13A1 gene (Protein Coding), Coagulation Factor XIII A Chain, including: function, proteins, disorders, pathways,
28 Jul 2020 Many reports illustrate that Coagulation factor XIIIa (FXIIIa) has diverse and crucial functions in thrombus for¬mation and stability.
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Factor XIIIa is a blood coagulation prototransglutaminase 1, which becomes an activated component of the final stages of the clotting cascade as a result of the interaction with thrombin and Ca 2+. Factor XIIIa is a dermal dendrocyte marker and shows variable reaction with these types of tumors. It can be used for histiocytic phenotyping and has been reported to mark capillary hemangiomas and tumors of the central nervous system.
Cell Marque. 251M-1.
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Biokemiska element. Biologiska biokemiska element
Ord. Factor XIIIa. Förklaring. 1. Farmakoloisk effekt. Kemisk struktur. Word.
Hedin CA, Gerner L, Magenta (N-terminal): activation peptide, which is removed when XIII is activated to XIIIa; Cyan: β-sandwich; Green: catalytic core (orange: catalytic amino acid Lockheed martin t-rex: preliminary report The contents are as follows: Electrical Considerations; General Electrical Consideration; Trailing Cables; Grounding; Tissue factor från skadad vävnad som trombocyter kan ta upp.
57, (24), 10355-10365 (2014). Postma Faktor XIIIa, som aktiveras från faktor XIII av trombin, tvärbinder fibrin. Factor XIIIa, which is activated from factor XIII by thrombin, crosslinks fibrin.